Pd2,6ST, recombinant (Photobacterium damsel)
CAt#
CBGEN00001
CAS#
9075-81-4
Abbr
Pd2,6ST, recombinant (Photobacterium damsel)
Source
E. coli
Species
Photobacterium damsel
Enzyme Commission Number
2.4.99.1
Molecular Weight
57 KDa
Purity
min 95% by SDS-PAGE
Physical Form
Supplied as a lyophilized powder
Package
1U,5U,25U
Description
Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide. Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N-or O-linked sugar chains of glycoproteins.
Unit Definition
One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol Siaα2,6Lac from CMP-Sia and Lactose per minute at 37 °C.
References
1. Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors Szczepanski A, et.al. Viruses 11(4), 328-328, (2019); 2. Enhanced Bacterial alpha (2, 6)-Sialyltransferase Reaction through an Inhibition of Its Inherent Sialidase Activity by Dephosphorylation of Cytidine-5'-Monophosphate Kang JY, et.al. PLoS ONE 10(7), e0133739-e0133739, (2015) 3. High-quality production of human alpha-2, 6-sialyltransferase in Pichia pastoris requires control over N-terminal truncations by host-inherent protease activities Ribitsch D, et.al. Microbial cell factories 13, 138-138, (2014)