L-fucokinase/GDP-fucose pyrophosphorylase (FKP)
CBGEN00010
Abbr
FKP, Recombinant (Bacteroides fragilis)
Source
E. coli
Species
Bacteroides fragilis
Enzyme Commission Number
2.7.1.52/2.7.730
Molecular Weight
106 KDa
Purity
min 95% by SDS-PAGE
Physical Form
Supplied as a lyophilized powder
Package
2U,10U,50U
Description
Catalyzes the ATP and L-Fucose to form Fuc-1-P.
Unit Definition
One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol Fuc-1-P from L-Fuc and ATP per minute at 37 °C.
References
1. Cryo-EM structure of L-fucokinase/GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis. Liu Y. et. al. Protein Cell, 10 (5), 365-369, 2019 2. Chemoenzymatic synthesis of GDP-l-fucose and the Lewis X glycan derivatives. Wei Wang et. al. PNAS, 106 (38), 16096-16101, 2009