Pasteurella multocida Hyaluronan synthase(PmHAS)
CBGEN00022
Abbr
PmHAS, Recombinant (Pasteurella multocida)
Source
E. coli
Species
Pasteurella multocida
Enzyme Commission Number
2.4.1.142
Molecular Weight
--
Purity
min 95% by SDS-PAGE
Physical Form
Supplied as a lyophilized powder
Package
1u,5u,10u
Description
The enzyme utilized UDP-sugar precursors of HA in the presence of Mg2+ or Mn2+ at neutral pH to synthesize Hyaluronic acid (HA), a linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues, is an essential molecule of higher vertebrates.
Unit Definition
PmHAS polymerizes Hyaluronan chain from UDP-GlcNAc and UDP-GlcA sugar nucleotide donors.
References
characterization of the Pasteurella multocida hyaluronic acid synthase. DeAngelis PL. et.al. Biochemistry. 35 (30), 9768-9771, 1996